Lysosome impairment as a trigger for inflammation in obesity: The proof is in the fat.

Autor: David R. Rawnsley, Abhinav Diwan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: EBioMedicine, Vol 56, Iss , Pp 102824- (2020)
Druh dokumentu: article
ISSN: 2352-3964
DOI: 10.1016/j.ebiom.2020.102824
Popis: Obesity is a global epidemic contributing to the rising prevalence of multiple disorders including metabolic syndrome, diabetes, fatty liver disease, cardiovascular and cerebrovascular disease, Alzheimer's disease and certain cancers. A renewed sense of urgency is required as obesity remains an intractable problem, despite a rapidly expanding armamentarium of behavioral, pharmacologic and surgical approaches which fall short of delivering sustained results
Databáze: Directory of Open Access Journals