Association between maternal gestation weight gain and preterm birth according to pre-pregnancy body mass index and HbA1c

Autor: Xiaoxiao Zhang, Binbin Yin, Kaiqi Wu, Lei Fang, Yan Chen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Obstetrics and Gynaecology, Vol 44, Iss 1 (2024)
Druh dokumentu: article
ISSN: 01443615
1364-6893
0144-3615
DOI: 10.1080/01443615.2024.2359671
Popis: Background To investigate the association between gestational weight gain (GWG) and preterm birth (PTB) according to pre-pregnancy body mass index (pp-BMI) and glycated haemoglobin (HbA1c) within the normal range.Methods We conducted a population-based retrospective cohort study between July 2017 and January 2020 at Women’s Hospital, Zhejiang University School of Medicine. Women were classified into three groups (inadequate GWG, appropriate GWG, and excessive GWG). In addition, women were divided into different subgroups according to pp-BMI and HbA1c. We estimated the odds ratios (OR) with 95% confidence intervals (CI) to assess the associations between GWG and the risk of PTB. Meanwhile, we adjusted for possible confounding factors, including maternal age, infant sex, family history of diabetes, education, pregnancy mode, delivery mode, parity, and gravidity.Results The study involved 23,699 pregnant women, of which 1124 (4.70%) were PTB. Women who had inadequate GWG were found to have a significantly higher risk of PTB compared to women with appropriate GWG. In contrast, women with excessive GWG had a reduced risk of PTB. Similarly, GWG and PTB had similar risk associations in the HbA1c and pp-BMI subgroups. Among women with pp-BMI
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