Cardiopulmonary bypass in a pediatric patient with factor XII deficiency

Autor: Fenske Julie M., Tinius Juliani Julie, Herrington Cynthia
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: The Journal of ExtraCorporeal Technology, Vol 56, Iss 3, Pp 125-127 (2024)
Druh dokumentu: article
ISSN: 0022-1058
2969-8960
DOI: 10.1051/ject/2024021
Popis: The safe use of cardiopulmonary bypass (CPB) relies upon the ability to administer, monitor, and reverse anticoagulation. Although rare, the factor XII deficient patient creates a challenge for the perfusionist due to resultant complications in monitoring anticoagulation. There have been proposed strategies to aid in monitoring anticoagulation in factor XII deficient patients, however, documentation of successful monitoring during CPB is infrequent. With the use of the Hemochron Signature Elite and ACT + cartridges, CPB in a factor XII deficient 8-month-old was completed with predictable and reliable anticoagulation monitoring. This case report explores the current suggestions for factor XII deficiency management with CPB.
Databáze: Directory of Open Access Journals