A multicenter retrospective study on the real-world outcomes of autologous vs. allogeneic hematopoietic stem cell transplantation for peripheral T-cell lymphoma in China
| Autor: | Zhen-Yang Gu, Yu-Jun Dong, Xiao-Rui Fu, Nai-Nong Li, Yao Liu, Xiao-Xiong Wu, Yi-Ni Wang, Yu-Hang Li, Han-Yun Ren, Ming-Zhi Zhang, Xiao-Fan Li, Mai-Hong Wang, Ya-Mei Wu, Dai-Hong Liu, Zhao Wang, Liang-Ding Hu, Wen-Rong Huang, Peng Lyu |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Chinese Medical Journal, Vol 134, Iss 13, Pp 1584-1592 (2021) |
| Druh dokumentu: | article |
| ISSN: | 0366-6999 2542-5641 00000000 |
| DOI: | 10.1097/CM9.0000000000001575 |
| Popis: | Abstract. Background:. There were few studies on real-world data about autologous hematopoietic stem cell transplantation (auto-HSCT) or allogeneic HSCT (allo-HSCT) in peripheral T-cell lymphoma (PTCL). This study aimed to investigate the clinical outcomes of patients who received auto-HSCT or allo-HSCT in China. Methods:. From July 2007 to June 2017, a total of 128 patients who received auto-HSCT (n = 72) or allo-HSCT (n = 56) at eight medical centers across China were included in this study. We retrospectively collected their demographic and clinical data and compared the clinical outcomes between groups. Results:. Patients receiving allo-HSCT were more likely to be diagnosed with stage III or IV disease (95% vs. 82%, P = 0.027), bone marrow involvement (42% vs. 15%, P = 0.001), chemotherapy-resistant disease (41% vs. 8%, P = 0.001), and progression disease (32% vs. 4%, P |
| Databáze: | Directory of Open Access Journals |
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