The Globular State of the Single-Stranded RNA: Effect of the Secondary Structure Rearrangements

Autor: Zareh A. Grigoryan, Armen T. Karapetian
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Journal of Nucleic Acids, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 2090-0201
2090-021X
DOI: 10.1155/2015/295264
Popis: The mutual influence of the slow rearrangements of secondary structure and fast collapse of the long single-stranded RNA (ssRNA) in approximation of coarse-grained model is studied with analytic calculations. It is assumed that the characteristic time of the secondary structure rearrangement is much longer than that for the formation of the tertiary structure. A nonequilibrium phase transition of the 2nd order has been observed.
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