Phytochemical inspection and anti-inflammatory potential of Euphorbia milii Des Moul. integrated with network pharmacology approach

Autor: Walaa A. Negm, Engy Elekhnawy, Fatma A. Mokhtar, Reem Binsuwaidan, Nashwah G.M. Attallah, Sally Abdallah Mostafa, Ehssan Moglad, Sarah Ibrahim, Omnia Momtaz Al-Fakhrany, Duaa Eliwa
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Arabian Journal of Chemistry, Vol 17, Iss 2, Pp 105568- (2024)
Druh dokumentu: article
ISSN: 1878-5352
DOI: 10.1016/j.arabjc.2023.105568
Popis: The inflammatory reaction is induced by several factors like stimulation of different enzymes, oxidative stress, and production of various proinflammatory mediators. Here, we elucidated the phytochemical profile of Euphorbia milii ethanol extract (EMEE) then, we studied its anti-inflammatory potential using a carrageenan-induced paw edema model in rats. It was found that the average paw edoema weight substantially declined (p
Databáze: Directory of Open Access Journals