Autor: |
Miao Sun, Min Liu, Faqiang Zhang, Lijuan Sang, Yuxiang Song, Peng Li, Siyuan Liu, Huikai Yang, Libin Ma, Jiangbei Cao, Weidong Mi, Yulong Ma |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-11 (2024) |
Druh dokumentu: |
article |
ISSN: |
1476-511X |
DOI: |
10.1186/s12944-024-02084-2 |
Popis: |
Abstract Background Postoperative delirium (POD) is more prevalent among elderly patients with type 2 diabetes mellitus (T2DM). Insulin resistance (IR) can be assessed using the triglyceride-glucose (TyG) index, a novel biomarker. This study aims to investigate the predictive potential of the TyG index for POD in elderly patients with T2DM. Materials and methods Elderly patients (≥ 65) with T2DM who underwent non-neurosurgery and non-cardiac surgery were enrolled. Univariate and multivariate logistic regression analyses were conducted to assess the association between the TyG index and POD. Additionally, subgroup analyses were performed to compare the sex-specific differences in the predictive ability of the TyG index for POD. Results A total of 4566 patients were included in this retrospective cohort. The receiver operating characteristic (ROC) curve analysis determined the optimal cut-off value for the TyG index to be 8.678. In the univariate model, a TyG index > 8.678 exhibited an odds ratio (OR) of 1.668 (95% CI: 1.210–2.324, P = 0.002) for predicting POD. In the multivariate regression models, the ORs were 1.590 (95% CI: 1.133–2.252, P |
Databáze: |
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