| Autor: |
Matteo Maspero, Peter R. Seevinck, Nicole J. W. Willems, Gonda G. Sikkes, Geja J. de Kogel, Hans C. J. de Boer, Jochem R. N. van der Voort van Zyp, Cornelis A. T. van den Berg |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Radiation Oncology, Vol 13, Iss 1, Pp 1-12 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
1748-717X |
| DOI: |
10.1186/s13014-018-1029-7 |
| Popis: |
Abstract Background The use of intraprostatic gold fiducial markers (FMs) ensures highly accurate and precise image-guided radiation therapy for patients diagnosed with prostate cancer thanks to the ease of localising FMs on photon-based imaging, like Computed Tomography (CT) images. Recently, Magnetic Resonance (MR)-only radiotherapy has been proposed to simplify the workflow and reduce possible systematic uncertainties. A critical, determining factor in the accuracy of such an MR-only simulation will be accurate FM localisation using solely MR images. Purpose The aim of this study is to evaluate the performances of manual MR-based FM localisation within a clinical environment. Methods We designed a study in which 5 clinically involved radiation therapy technicians (RTTs) independently localised the gold FMs implanted in 16 prostate cancer patients in two scenarios: employing a single MR sequence or a combination of sequences. Inter-observer precision and accuracy were assessed for the two scenarios for localisation in terms of 95% limit of agreement on single FMs (LoA)/ centre of mass (LoA CM) and inter-marker distances (IDs), respectively. Results The number of precisely located FMs (LoA |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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