Pseudotumoral form of granulomatosis with polyangiitis

Autor: Fadwa Mekouar, Naoual El Omri
Jazyk: English<br />French
Rok vydání: 2017
Předmět:
Zdroj: The Pan African Medical Journal, Vol 26, Iss 173 (2017)
Druh dokumentu: article
ISSN: 1937-8688
DOI: 10.11604/pamj.2017.26.173.12195
Popis: A 65-year-old woman, non-smoker presented with a two-month history of cough. She also complained of arthralgia and weight loss. The clinical examination revealed a febrile patient. The chest radiograph and the scanner revealed right upper lobar mass, with spiculated contours (A, B). Biology showed an inflammatory syndrome. Polymerase chain reaction for Mycobacterium tuberculosis and tumor markers was negative. A lung biopsy showed non caseous granulomatous vasculitis. The cytoplasmic antineutrophil cytoplasmic antibody (cANCA/PR3/ANCA) showed a positive result; Wegener's granulomatosis was finally confirmed. The patient was treated with prednisone and cyclophosphamide with favorable outcome. A follow-up chest radiography two weeks after treatment showed resolving pulmonary lesions (C).
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