Tumor-to-Tumor Metastases Involving Clear Cell Renal Cell Carcinomas: A Diagnostic Challenge for Pathologists Needing Clinical Correlation

Autor: Claudia Manini, Claudia Provenza, Leire Andrés, Igone Imaz, Rosa Guarch, Raffaelle Nunziata, José I. López
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Clinics and Practice, Vol 13, Iss 1, Pp 288-296 (2023)
Druh dokumentu: article
ISSN: 13010026
2039-7283
DOI: 10.3390/clinpract13010026
Popis: Tumor-to-tumor metastasis is a rare event which it is specifically up to pathologists to bring to light correctly. The histological identification of such tumor-to-tumor cases is simple when the respective histologies are different but can be problematic if the case includes two carcinomas with similar cytoarchitecture viewed one inside the other under the microscope. We report four cases of this condition in which clear cell renal cell carcinoma is involved, either as a receptor or as a donor, and remark on the difficulties in recognizing some of them. Appropriate clinical–pathological correlation, including a review of the patient’s antecedents and radiological exams, would be a great help in routinely identifying tumor-to-tumor metastases.
Databáze: Directory of Open Access Journals
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