| Autor: |
Kevin Kuo, Yu-Xiang Yang, Ya-Ru Zhang, Shi-Dong Chen, Shu-Yi Huang, Bang-Sheng Wu, Jin-Tai Yu |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Brain Disorders, Vol 7, Iss , Pp 100047- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-4593 |
| DOI: |
10.1016/j.dscb.2022.100047 |
| Popis: |
Introduction: Heart failure has been shown to be associated with an increased risk of dementia and its subtype- Alzheimer's disease in observational studies. However, whether this associations reflects the underlying causality remains controversial. This study aims to investigate the causal effects of heart failure on the risk of Alzheimer's disease. Materials and Methods: We conducted a two-sample Mendelian randomization analysis using summary data from recently published genome-wide association studies. Twelve single nucleotide polymorphisms (SNPs) associated with heart failure at a significance level of P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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