| Autor: |
Hiroki Yoshimatsu, Takayuki Imaeda, Shingo Higa, Keisuke Nomoto |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Health Science Reports, Vol 6, Iss 9, Pp n/a-n/a (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2398-8835 |
| DOI: |
10.1002/hsr2.1512 |
| Popis: |
Abstract Background and Aims The Children's Depression Rating Scale‐Revised (CDRS‐R) score has been widely used to assess the severity of major depression in children and adolescents; however, the clinical implications of changes in the CDRS‐R score remain unclear. We evaluated these clinical implications by assessing the relationship between changes in the CDRS‐R score and changes in the Clinical Global Impression of Improvement (CGI‐I), in clinical research on major depression. Methods We used data from four clinical trials involving two antidepressants and evaluated the relationship between CDRS‐R score changes and the CGI‐I score using the equipercentile linking method. Results CDRS‐R score changes corresponding to a minimally improved (score of 3) CGI‐I score was approximately 14 points. Conclusion Our findings from the linking analyses are useful for interpreting the clinical implications of changes in the CDRS‐R score. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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