Efficacy of Perineural versus Systemic Dexmedetomidine as an Adjuvant to Bupivacaine for Surgical Anesthesia in Axillary Block

Autor: Kaukab Majeed, Amran Hafiz, Usman Eijaz Malik, Fayyaz Hussain, Najm Us Saqib, Amna Gulraz
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pakistan Armed Forces Medical Journal, Vol 73, Iss 4 (2023)
Druh dokumentu: article
ISSN: 0030-9648
2411-8842
DOI: 10.51253/pafmj.v73i4.8506
Popis: Objective: To compare the analgesic effect of different routes of Dexmedetomidine when given as an adjuvant to Bupivacaine in the axillary block for surgical correction of radius fracture. Study Design: Quasi-experimental study. Place and Duration of Study: Pak Emirates Military Hospital, Rawalpindi Pakistan, from Sep 2021 to Feb 2022. Methodology: The patients were divided into two equal groups. Group-A (Perineural Dexmedetomidine) and Group B (Intravenous Dexmedetomidine). Group-A received 1ug/kg Perineural Dexmedetomidine along with 30ml of racemic Bupivacaine (0.5%), and Group-B participants received 1ug per kg intravenous Dexmedetomidine after axillary block with 30ml of 0.5% perineural racemic Bupivacaine. The mean duration of analgesia was the primary outcome, and adverse outcomes and sedation were the secondary outcomes. Results: The duration of analgesia was greater in the perineural Dexmedetomidine Group, with a mean duration of 610.20±29.92 minutes in comparison to the systemic Dexmedetomidine Group, which was 449±39.010 minutes, with pvalue
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