| Autor: |
Yuriko Iwahata, Junichi Hasegawa, Chika Homma, Hideyuki Iwahata, Natsumi Furuya, Haruhiro Kondo, Nao Suzuki |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Clinical and Experimental Obstetrics & Gynecology, Vol 49, Iss 5, p 101 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
0390-6663 |
| DOI: |
10.31083/j.ceog4905101 |
| Popis: |
Background: To evaluate the impact perinatal factors closely related to the development of neonatal intraventricular hemorrhage (IVH) in preterm infants. Methods: A retrospective case-control study was performed on premature infants born in our perinatal center in 2014–2018. Neonates with IVH were age-matched with normal controls (1:5). Perinatal factors were compared between cases and controls. Results: Fourteen cases and 70 controls had a median of 26.5 (range 22–29) weeks gestational age. Significant difference was observed regarding the incidence of clinical chorioamnionitis (43% and 14%, p = 0.023) and the use of magnesium sulfate (MgSO4) (14% and 51%, p = 0.017). Adjusted odds ratios (95% confidence interval) were 8.3 (1.8–38) in clinical chorioamnionitis and 0.15 (0.03–0.76) in magnesium sulfate. Conclusions: Relevant perinatal factor of IVH in premature infants born before 30 weeks of gestation was strongly associated with clinical chorioamnionitis. Furthermore, MgSO4 exposure suggested a neuroprotective effect against IVH. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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