Impact of maternal age and body mass index on the structure and function of the heart in newborns: a Copenhagen Baby Heart Study

Autor:	Mette Marie Olsen Nørregaard, Saima Basit, Anne-Sophie Sillesen, Anna Axelsson Raja, Finn Stener Jørgensen, Kasper Karmark Iversen, Henning Bundgaard, Heather Allison Boyd, Ruth Ottilia Birgitta Vøgg
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Newborn heart Maternal factors Body mass index Maternal age Echocardiography Medicine
Zdroj:	BMC Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Druh dokumentu:	article
ISSN:	1741-7015
DOI:	10.1186/s12916-023-03207-9
Popis:	Abstract Background Maternal obesity and advanced age have been associated with an increased risk of structural congenital heart defects in the offspring. Whether these factors may also cause abnormalities in infant cardiac dimension and function is unknown. This study investigates whether maternal body mass index (BMI) and maternal age are associated with changes in left ventricular (LV) dimensions and function in the newborn. Methods Infants enrolled in the Copenhagen Baby Heart Study (CBHS), who were born at term, and contributed with a transthoracic echocardiography (TTE) within 60 days of birth were included. The exposure variables were prepregnancy maternal BMI (kg/m2)
Databáze:	Directory of Open Access Journals
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