Acute Fatal Hemorrhage-Induced Activation of Lipid Peroxidation Processes and Cardiac Lesion
| Autor: | V. T. Dolgikh, F. I. Razgonov, L. G. Shikunova |
|---|---|
| Jazyk: | English<br />Russian |
| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Общая реаниматология, Vol 2, Iss 6, Pp 50-54 (2006) |
| Druh dokumentu: | article |
| ISSN: | 1813-9779 2411-7110 |
| DOI: | 10.15360/1813-9779-2006-6-50-54 |
| Popis: | The time course of changes in myocardial lipid peroxidation processes was studied in an experiment on albino male rats that had experienced 4-minute clinical death. There was an alternation of periods of a significant increase (minute 90, hours 3—6, and days 1—3 and 14) and a decrease (days 7, 21, and 30) in the rate of lipoprotein processes and corresponding changes in the content of lipid hydroperoxides and Schiff s bases. Activation of lipid peroxidation processes occurred with deficiency of bioantioxidants and with inhibition of enzymes that made antiradical and antiperoxide protection of cardiomyocytes.acute fatal hemorrhage; resuscitation; heart; lipid peroxidation |
| Databáze: | Directory of Open Access Journals |
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