Evaluation of the clinical efficacy of local antibacterial therapy in the treatment of acute bacterial rhinosinusitis
Autor: | T. V. Banashek-Meshcheriakova, F. V. Semyonov |
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Jazyk: | ruština |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | Терапевтический архив, Vol 92, Iss 12, Pp 155-159 (2020) |
Druh dokumentu: | article |
ISSN: | 0040-3660 2309-5342 00403660 |
DOI: | 10.26442/00403660.2020.12.000834 |
Popis: | Aim.To evaluate the clinical efficacy of Polydexa with phenylephrinum in the complex treatment of moderate acute bacterial rhinosinusitis. Materials and methods.The article presents the results of a clinical study of 100 patients with moderate acute bacterial rhinosinusitis 37 (37%) men, 63 (63%) women aged 15 to 53 years. The patients were randomized into 2 groups of 50 people each. In the study group, patients received systemic antibiotic therapy and a topical nasal spray of Polydexa with phenylephrinum. The control group received systemic antibacterial therapy and long-acting local decongestants. The evaluation criteria were statistically significant differences in clinical and laboratory parameters of the control and main groups. Results and conclusion.The pronounced anti-inflammatory, antimicrobial effects of the drug were confirmed; conclusions were drawn about the clinical efficacy, tolerability, safety of Polydexa with phenylephrinum and allows to achieve complete resolution of the pathological process in more cases. |
Databáze: | Directory of Open Access Journals |
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