Investigations of the prevalence and virulence of Candida albicans in periodontal and endodontic lesions in diabetic and normoglycemic patients
| Autor: | Cinthya Cristina GOMES, Ludmila Silva GUIMARÃES, Larissa Christina Costa PINTO, Gabriela Alessandra da Cruz Galhardo CAMARGO, Maria Isabel Bastos VALENTE, Maria Inêz de Moura SARQUIS |
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| Jazyk: | angličtina |
| Předmět: | |
| Zdroj: | Journal of Applied Oral Science, Vol 25, Iss 3, Pp 274-281 |
| Druh dokumentu: | article |
| ISSN: | 1678-7765 1678-7757 |
| DOI: | 10.1590/1678-7757-2016-0432 |
| Popis: | Abstract Pulpal and periodontal tissues have similar microbiota that allows cross-contamination between the pulp and periodontal tissues. Objective The aim of this study was to investigate the prevalence of isolated Candida albicans from periodontal endodontic lesions in diabetic and normoglycemic patients, and the fungi's virulence in different atmospheric conditions. Material and Methods A case-control study was conducted on 15 patients with type 2 diabetes mellitus (G1) and 15 non-diabetics (G2) with periodontal endodontic lesions. Samples of root canals and periodontal pockets were plated on CHROMagar for later identification by polymerase chain reaction (PCR) and virulence test. Results C. albicans was identified in 79.2% and 20.8% of the 60 samples collected from diabetic and normoglycemic patients, respectively. Of the 30 samples collected from periodontal pockets, 13 showed a positive culture for C. albicans, with 77% belonging to G1 and 23% to G2. Of the 11 positive samples from root canals, 82% were from G1 and 18% from G2. Production of proteinase presented a precipitation zone Pz |
| Databáze: | Directory of Open Access Journals |
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