Active polyketides isolated from Penicillium herquei
| Autor: | ANDREY M.R. MARINHO, PATRICIA S.B. MARINHO, LOURIVALDO S. SANTOS, EDSON RODRIGUES FILHO, IZABEL C.P. FERREIRA |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Anais da Academia Brasileira de Ciências, Vol 85, Iss 3, Pp 909-912 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1678-2690 0001-3765 |
| DOI: | 10.1590/S0001-37652013005000048 |
| Popis: | In this work we are reporting the isolation by classical methods of chromatography of six polyketides from Penicillium herquei. The compounds citreorosein ( 1) , emodin ( 2) , janthinone ( 3) , citrinin ( 4) , citrinin H1 ( 5) and dicitrinol ( 6) were identified by spectral methods of 1D and 2D NMR and MS. Compounds 1, 2 and 3 were tested against promastigotes forms of Leishmania brasiliensis and 1 and 2 were also assayed against Escherichia coli, Pseudomonas aeruginosa and Bacillus subtilis and showed good activity. |
| Databáze: | Directory of Open Access Journals |
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