Association between neutrophil to high-density lipoprotein cholesterol ratio (NHR) and depression symptoms among the United States adults: a cross-sectional study

Autor: Guangwei Qing, Cheng Bao, Yuanjian Yang, Bo Wei
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1476-511X
DOI: 10.1186/s12944-024-02204-y
Popis: Abstract Background Depression acts as a noteworthy worldwide public health challenge. Identifying accessible biomarkers is crucial for early diagnosis and intervention. The relationship between depression in adult Americans and the neutrophil to high-density lipoprotein cholesterol ratio (NHR) was investigated in this research. Methods The relationship between NHR and depressive symptoms was analyzed utilizing National Health and Nutrition Examination Survey data from 2005 to 2018 and the Patient Health Questionnaire-9. The study included 33,871 participants with complete NHR and depression data. Adjusted multivariable logistic regression models were used to account for possible confounders, and subgroup analyses were conducted to investigate effect changes. Results Elevated NHR levels were positively correlated with a heightened risk of depression (OR = 1.03, 95% CI: 1.01–1.05, P
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