Salmonellacidal antibody response to Salmonella enterica serovar Typhi in enteric fever and after vaccination with Vi capsular polysaccharide

Autor: Lovely Barai, Md. Rokibul Hasan, Jalaluddin Ashraful Haq, Chowdhury Rafiqul Ahsan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: International Journal of Infectious Diseases, Vol 121, Iss , Pp 120-125 (2022)
Druh dokumentu: article
ISSN: 1201-9712
DOI: 10.1016/j.ijid.2022.05.022
Popis: Objectives: Serum salmonellacidal (bactericidal) antibody could be used to detect functional capacity of antibody in patients with enteric fever and after typhoid vaccination. Methods: Salmonellacidal antibody response was measured by colorimetric serum salmonellacidal assay from 70 acute and 11 convalescence sera of patients infected with Salmonella Typhi and Paratyphi A and also from 15 control and 6 Vi capsular polysaccharide vaccinated volunteer's sera. Results: Sera from patients with typhoid and paratyphoid A showed significant (p < 0.05) levels of salmonellacidal antibody titer (549.9 ± 108.5 and 528.7 ± 187.3) compared with control (0.133 ± 0.1). Moreover, this titer increased significantly (p
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