Autor: |
Xiaohui Zhang, Yanxia Qi, Youzhi Pang, Bingjie Yuan, Xiaolong Li |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
The Journal of Poultry Science, Vol 60, Iss 2 (2023) |
Druh dokumentu: |
article |
ISSN: |
1349-0486 |
DOI: |
10.2141/jpsa.2023013 |
Popis: |
Mutations in the HERC2 and OCA2 genes have the potential to affect pigment deposition and alter feather color in birds. Therefore, in this study, we evaluated HERC2-OCA2 gene locus polymorphisms in Korean and Beijing white quails using RNA-Seq and KASP technology. The expression levels of HERC2 and OCA2 mRNA in skin tissues were analyzed using RT-qPCR. Ten single nucleotide polymorphisms were identified by RNA-Seq, of which three (n.117627564T>A, n.117674275T>G, n.117686226A>C) exhibited significant association with feather color in quail. The expression of OCA2 mRNA was significantly lower in the skin of Beijing white quails than that in the skin of Korean quails. These results suggested that variants in HERC2-OCA2 intergenic region could influence the expression of OCA2, which may underlie diluted feather color in the Beijing white quail. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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