Clinical and Microbiological Risk Factors for Community-Associated Clostridioides difficile Infections
| Autor: | Young Ah Kim, Heejung Kim, Dokyun Kim, Changseung Liu, Seok Hoon Jeong |
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| Jazyk: | English<br />Korean |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Annals of Clinical Microbiology, Vol 25, Iss 2, Pp 53-58 (2022) |
| Druh dokumentu: | article |
| ISSN: | 2288-0585 2288-6850 |
| DOI: | 10.5145/ACM.2022.25.2.3 |
| Popis: | Background: The incidence of community-associated (CA) Clostridioides difficile infection (CDI) has increased in Korea. In this study, we evaluated CA-CDI risk factors in terms of clinical features and ribotype considering its region-specific molecular epidemiology. Methods: A retrospective case-control study was performed on two groups of CDI patients: 127 subjects with CA-CDI and 265 subjects with healthcare-associated (HA)-CDI. Risk factors for CA-CDI were evaluated in terms of clinical and microbiological features such as toxin type and ribotype. Results: A comparison of the two groups of CDI patients revealed that inflammatory bowel disease, diarrhea, abdominal pain, and fever were more closely associated with CA-CDI. The toxin types and ribotypes of C. difficile were similar between the two groups. After adjusting for variables, no risk factors were identified for CA-CDI compared with HA-CDI. Conclusion: Specific risk factors for CA-CDI were not identified in this study. |
| Databáze: | Directory of Open Access Journals |
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