| Autor: |
Alejandro E. Contreras, Facundo Ledesma, Alejandro R. Peirone, Ernesto Juaneda, Victor Defago, Eduardo Cuestas |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Indian Heart Journal, Vol 75, Iss 2, Pp 145-152 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
0019-4832 |
| DOI: |
10.1016/j.ihj.2023.01.008 |
| Popis: |
Background: The aim of this meta-analysis was to compare the efficacy and adverse events of percutaneous occlusion among patients with sufficient and deficient rims. Methods: A systematic review of all articles published in the Pubmed, MEDLINE and Google Scholar databases was performed. Odds ratio (OR) and 95% CI were used as a measure of effect of the combination of studies. I2 with 95% CI was estimated to assess study heterogeneity. For the meta-analysis, a random effects model was used. Results: The systematic search identified ten studies which included 4355 patients; 2661 of those had sufficient rim and the remaining 1694 patients showed some rim deficiency. Implant failure rate was 4.13% CI 95% 3.53–4.72%. Compared to frequency of failures in the group with a deficient rim (5.43% CI 95% 4.35–6.50%), implant failure in patients with a sufficient rim was significantly lower (3.30% CI 95% 2.62–3.97%), OR 2.27 CI 1.34–3.83 (p 0.002).The combined adverse events were 5.19% CI 95% 4.22–6.35% vs 2.7% CI 95% 2.08–3.31% in the deficient vs sufficient rim groups respectively (OR 2.21 CI 0.93–5.29; p 0.07). Implant failures and adverse events were more frequent in patients with posterior inferior rim deficiency. Conclusion: Patients presenting a posteroinferior rim deficiency are associated to both, an increased incidence of closure failure and a combined adverse events occurrence. More studies on posterior rim deficiency are necessary to ensure the feasibility and safety of the percutaneous approach. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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