| Autor: |
Jade C. Riopelle, Amirhossein Shamsaddini, Myndi G. Holbrook, Eric Bohrnsen, Yue Zhang, Jamie Lovaglio, Kathleen Cordova, Patrick Hanley, Lon V. Kendall, Catharine M. Bosio, Tony Schountz, Benjamin Schwarz, Vincent J. Munster, Julia R. Port |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2045-2322 |
| DOI: |
10.1038/s41598-024-53645-5 |
| Popis: |
Abstract The intestinal microbiome plays an important role in mammalian health, disease, and immune function. In light of this function, recent studies have aimed to characterize the microbiomes of various bat species, which are noteworthy for their roles as reservoir hosts for several viruses known to be highly pathogenic in other mammals. Despite ongoing bat microbiome research, its role in immune function and disease, especially the effects of changes in the microbiome on host health, remains nebulous. Here, we describe a novel methodology to investigate the intestinal microbiome of captive Jamaican fruit bats (Artibeus jamaicensis). We observed a high degree of individual variation in addition to sex- and cohort-linked differences. The intestinal microbiome was correlated with intestinal metabolite composition, possibly contributing to differences in immune status. This work provides a basis for future infection and field studies to examine in detail the role of the intestinal microbiome in antiviral immunity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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