Aluminum Silicate Nanotube Modification of Cotton-Like Siloxane-poly(L-lactic acid)-vaterite Composites

Autor: Daiheon Lee, Hirotaka Maeda, Akiko Obata, Keiichi Inukai, Katsuya Kato, Toshihiro Kasuga
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Advances in Materials Science and Engineering, Vol 2013 (2013)
Druh dokumentu: article
ISSN: 1687-8434
1687-8442
DOI: 10.1155/2013/169721
Popis: In our earlier work, a cotton-like biodegradable composite, consisting of poly(L-lactic acid) with siloxane-containing vaterite, has been prepared by electrospinning. In the present work, the fibers skeleton of the cotton-like composites was modified successfully with imogolite, which is hydrophilic and biocompatible, via a dip process using ethanol diluted solution to improve the cellular initial attachment. Almost no change in the fiber morphology after the surface modification was observed. The surface-modified composite showed the similar calcium and silicate ions releasabilities, for activating the osteoblasts, as an unmodified one. Cell culture tests showed that the initial adhesion of murine osteoblast-like cells on the surface of the fibers was enhanced by surface modification.
Databáze: Directory of Open Access Journals