Sex disparities of the effect of the COVID-19 pandemic on mortality among patients living with tuberculosis in the United States

Autor: Huan Deng, Yishan Liu, Fan Lv, Xiaofeng Li, Mingyan Qi, Yajing Bo, Sikai Qiu, Xinyuan He, Fanpu Ji, Qing-Lei Zeng, Ning Gao
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Public Health, Vol 12 (2024)
Druh dokumentu: article
ISSN: 2296-2565
DOI: 10.3389/fpubh.2024.1413604
Popis: BackgroundWe aimed to determine the trend of TB-related deaths during the COVID-19 pandemic.MethodsTB-related mortality data of decedents aged ≥25 years from 2006 to 2021 were analyzed. Excess deaths were estimated by determining the difference between observed and projected mortality rates during the pandemic.ResultsA total of 18,628 TB-related deaths were documented from 2006 to 2021. TB-related age-standardized mortality rates (ASMRs) were 0.51 in 2020 and 0.52 in 2021, corresponding to an excess mortality of 10.22 and 9.19%, respectively. Female patients with TB demonstrated a higher relative increase in mortality (26.33 vs. 2.17% in 2020; 21.48 vs. 3.23% in 2021) when compared to male. Female aged 45–64 years old showed a surge in mortality, with an annual percent change (APC) of −2.2% pre-pandemic to 22.8% (95% CI: −1.7 to 68.7%) during the pandemic, corresponding to excess mortalities of 62.165 and 99.16% in 2020 and 2021, respectively; these excess mortality rates were higher than those observed in the overall female population ages 45–64 years in 2020 (17.53%) and 2021 (33.79%).ConclusionThe steady decline in TB-related mortality in the United States has been reversed by COVID-19. Female with TB were disproportionately affected by the pandemic.
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