Cardiac magnetic resonance imaging R2* assessments and analysis of historical parameters in patients with transfusion-dependent thalassemia

Autor:	Athanassios Aessopos, Christina Fragodimitri, Fotios Karabatsos, Antonia Hatziliami, Jacqueline Yousef, Anastasios Giakoumis, Aikaterini Dokou, Efstathios D. Gotsis, Vasilis Berdoukas, Markissia Karagiorga
Jazyk:	angličtina
Rok vydání:	2007
Předmět:	Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Haematologica, Vol 92, Iss 1 (2007)
Druh dokumentu:	article
ISSN:	0390-6078 1592-8721
DOI:	10.3324/haematol.10455
Popis:	Recent advances in magnetic resonance imaging (MRI) techniques allow the assessment of iron overload in tissues1 especially the heart,2 in transfusion- dependent thalassemia patients. The R2* value (1/T2*) recorded in the intraventricular septum of the heart indirectly measures the degree of cardiac iron load. Applying this new technology we looked at a number of historical and biochemical parameters in order to determine their relationship to cardiac iron overload and the effect of cardiac iron on functional and structural changes of the heart in transfusion-dependent thalassemics.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3edabd3429d946128099dffa14937905 Zobrazit plný text záznamu View record in DOAJ