Nucleoside-Lipid-Based Nanocarriers for Sorafenib Delivery

Autor:	Sebastien Benizri, Ludivine Ferey, Bruno Alies, Naila Mebarek, Gaelle Vacher, Ananda Appavoo, Cathy Staedel, Karen Gaudin, Philippe Barthélémy
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Sorafenib Solid lipid nanoparticles Nucleolipids Hepatocarcinoma Breast carcinoma Luminal B Materials of engineering and construction. Mechanics of materials TA401-492
Zdroj:	Nanoscale Research Letters, Vol 13, Iss 1, Pp 1-8 (2018)
Druh dokumentu:	article
ISSN:	1931-7573 1556-276X
DOI:	10.1186/s11671-017-2420-2
Popis:	Abstract Although the application of sorafenib, a small inhibitor of tyrosine protein kinases, to cancer treatments remains a worldwide option in chemotherapy, novel strategies are needed to address the low water solubility ( 80 μM) revealed a total cancer cell death in all cases. These results highlight the potential of nucleoside-lipid-based SLNs as drug delivery systems.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3ed3a3434d904302975566ed31bf2705 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ