Lymphoepithelioma-like carcinoma of the vulva, an underrecognized entity? Case report with a single inguinal micrometastasis detected by sentinel node technique

Autor: Stummvoll Wolfgang, Roithmeier Franz, Gruber Christine, Haitchi-Petnehazy Sophie, Bösmüller Hans, Webersinke Gerald
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Diagnostic Pathology, Vol 6, Iss 1, p 4 (2011)
Druh dokumentu: article
ISSN: 1746-1596
DOI: 10.1186/1746-1596-6-4
Popis: Abstract This report describes an unusual EBV-negative lymphoepithelioma-like carcinoma of the vulva in a 73-year-old patient. The lesion was localised at the right minor labium and was resected by partial vulvectomy. A synchronous sentinel lymph node biopsy revealed a single micrometastasis in the right inguinal region, which prompted local radiotherapy. Follow-up nine months later showed only slight vulvar atrophy, without signs of local recurrence or distant metastases. Although lymphoepithelioma-like carcinomas of the skin and the female genital tract are presumed to have a better prognosis than their counterparts in the upper aerodigestive tract, possibly due to earlier detection and therapy, this case documents their potential for early metastasis.
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