DETERMINATION OF BREAKDOWN OF PRODUCTION OF ACTIVE FORMS OF OXYGEN AND CONTENT OF LIPIDS HYDROPEROXIDES IN HOMOGENATES OF CICATRICAL TISSUES IN DIFFERENT TERMS OF POSTALOPERATIVE PERIOD

Autor: Krinichko L. R., Lokes K. P., Stavitsky S. O., Grigorov S. I. S. I., Voloshina L. I.
Jazyk: English<br />Russian<br />Ukrainian
Rok vydání: 2018
Předmět:
Zdroj: Вісник проблем біології і медицини, Vol 1, Iss 4, Pp 95-98 (2018)
Druh dokumentu: article
ISSN: 2077-4214
2523-4110
DOI: 10.29254/2077-4214-2018-4-1-146-95-98
Popis: The aim of the study. The article is devoted to the study of biochemical mechanisms of regulation of regeneration processes after surgical incisions of the skin. The material for the biochemical study was the homogenate of the scar tissue and the intact skin (control group) obtained after surgical excision of scars and excess skin during surgical interventions of the neck cysts of the embryonic origin. Objects and methods of the study. It was studied the dynamics of changes in the active forms of oxygen (AFO) in the skin homogenate of different experimental groups. The result of study. It was found that in patients who received PRF-clot (first group) during surgery, the percentage of AFO in 3 months of supervision was significantly lower by 26.6%, after 6 months - by 10.9% and 9 months later - by 12.2% relative to the patients data of the control group. In patients of the first and third groups, after 12 months of observation, the percentage of AFO practically was not different. The level of the researched index varied during the observation period. Thus, in patients who received a PRFclot during surgery, after 6 months the percentage of AFO was by 18.5% lower, relatively to the data of the previous observation period, after 9 months - by 16.2% (p
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