Handheld motorized injection system with fiber-optic distance sensors and adaptive time-delay controller

Autor: Jintaek Im, Sukho Park, Cheol Song
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Optomechatronics, Vol 18, Iss 1 (2024)
Druh dokumentu: article
ISSN: 15599612
1559-9620
1559-9612
DOI: 10.1080/15599612.2023.2299023
Popis: During the last decade, many ophthalmic therapeutic drugs have been clinically approved, and intraocular injection has been a common surgical intervention. Injecting drugs directly into the subretinal space is crucial to treat retinal complications effectively. Here, we report a handheld microinjector with two fiber-optic distance sensors and time-delay control (TDC) to mitigate nonlinear disturbances during the injection task. The conventional method exhibited a cosine error of approximately 77 μm at an angle of 45°, whereas our proposed needle reduced measurement errors to ∼6 μm. Also, TDC-based position regulation is designed to adaptively apply motor inputs by estimating disturbances during the handheld task and achieving fast system responses with minor control errors. Phantom studies show a maximum reduction of 26.5% in root-mean-square error (RMSE) compared to the existing approach. Moreover, ex-vivo experiments demonstrated superior and robust injection performance, resulting in an injection RMSE of 10.3 μm.
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje