Lower urinary tract transitional cell carcinoma in cats: Clinical findings, treatments, and outcomes in 118 cases

Autor: Maureen A. Griffin, William T. N. Culp, Michelle A. Giuffrida, Peter Ellis, Joanne Tuohy, James A. Perry, Allison Gedney, Cassie N. Lux, Milan Milovancev, Mandy L. Wallace, Jonathan Hash, Kyle Mathews, Julius M. Liptak, Laura E. Selmic, Ameet Singh, Carrie A. Palm, Ingrid M. Balsa, Philipp D. Mayhew, Michele A. Steffey, Robert B. Rebhun, Jenna H. Burton, Michael S. Kent
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Veterinary Internal Medicine, Vol 34, Iss 1, Pp 274-282 (2020)
Druh dokumentu: article
ISSN: 1939-1676
0891-6640
DOI: 10.1111/jvim.15656
Popis: Abstract Background Lower urinary tract transitional cell carcinoma (TCC) is an important but rarely described disease of cats. Objectives To report the clinical characteristics, treatments, and outcomes in a cohort of cats with lower urinary tract TCC and to test identified variables for prognostic relevance. Animals One‐hundred eighteen client‐owned cats with lower urinary tract carcinoma. Methods Medical records were retrospectively reviewed to obtain information regarding clinical characteristics, treatments, and outcomes. Recorded variables were analyzed statistically. Results Median age of affected cats was 15 years (range, 5.0‐20.8 years) and median duration of clinical signs was 30 days (range, 0‐730 days). The trigone was the most common tumor location (32/118; 27.1%) as assessed by ultrasound examination, cystoscopy, or both. Treatment was carried out in 73 of 118 (61.9%) cats. Metastatic disease was documented in 25 of 118 (21.2%) cats. Median progression‐free survival and survival time for all cats were 113 days (95% confidence interval [CI], 69‐153) and 155 days (95% CI, 110‐222), respectively. Survival increased significantly (P
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