Changes in use and outcomes after fibrinogen concentrate insurance coverage for critical obstetrical hemorrhage: a nationwide questionnaire survey in Japan

Autor:	Masafumi Nii, Tomoaki Oda, Mamoru Morikawa, Yasushi Nakabayashi, Tomoko Adachi, Takao Kobayashi, Atsuo Itakura
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Critical obstetrical hemorrhage Fibrinogen concentrates Public medical insurance coverage Red blood cell concentrate Pulmonary edema Transfusion-induced allergy Medicine Science
Zdroj:	Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Druh dokumentu:	article
ISSN:	2045-2322
DOI:	10.1038/s41598-024-57244-2
Popis:	Abstract Fibrinogen concentrate (FC) for acquired hypofibrinogenemia associated with critical obstetrical hemorrhage (COH) was covered by public medical insurance in September 2021 in Japan. We aimed to investigate changes in the policy of FC use and its effect on COH after insurance coverage. A primary survey covering September 2020 to August 2021 and a secondary survey covering September 2021 to August 2022 were conducted at 428 higher-level medical facilities. We investigated the policy of FC use in transfusion strategy and the maternal outcomes in COH. Among the hospitals that responded to both surveys, the number of facilities that use FC increased from 51.5 (101/196) to 78.6% (154/196) (P
Databáze:	Directory of Open Access Journals
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