Chinese Xibe population genetic composition according to linkage groups of X-chromosomal STRs: population genetic variability and interpopulation comparisons

Autor: Hao-Tian Meng, Chun-Mei Shen, Yu-Dang Zhang, Qian Dong, Yu-Xin Guo, Guang Yang, Jiang-Wei Yan, Yao-Shun Liu, Ting Mei, Jian-Feng Shi, Bo-Feng Zhu
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Annals of Human Biology, Vol 44, Iss 6, Pp 546-553 (2017)
Druh dokumentu: article
ISSN: 0301-4460
1464-5033
03014460
DOI: 10.1080/03014460.2017.1318951
Popis: Background: The Xibe population is one of China’s officially recognised populations and is now distributed separately from west to east in the northern part of China. X-chromosomal short tandem repeats have a special inheritance pattern, and could be used as complements in forensic application, especially for complex or deficiency cases. Subjects and methods: This study obtained the allelic and haplotypic frequencies of 19 X-STR loci in the Xibe population from Xinjiang Uygur Autonomous Region, China, and studied the genetic differentiations between the Xibe and other populations. Results: The combined power of discrimination in females and males and mean exclusion chances in deficiency cases, normal trios and duo cases was at least 0.999 999 994. In the haplotypic study, the Xibe population showed a more similar pattern of haplotype distribution with Asian populations than populations from other continents, while allelic study also indicated a closer relationship between the Xibe and Asian populations. Conclusions: The 19 X-STR loci would be useful in forensic application in the studied population. The Xibe population showed a closer genetic relationship with Asian populations in the study, and more population data would be necessary for more detailed genetic relationship studies.
Databáze: Directory of Open Access Journals
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