| Autor: |
Jennifer L. Phillips, Pierre Blier, Jeanne Talbot |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Journal of Affective Disorders Reports, Vol 14, Iss , Pp 100613- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2666-9153 |
| DOI: |
10.1016/j.jadr.2023.100613 |
| Popis: |
Background: Despite advances in treatments for depression, approximately one third of patients do not benefit from available therapies. Intravenous ketamine is a novel intervention that can yield rapid yet transient antidepressant effects. Behavioural activation (BA) therapy for depression has been shown to be effective in preventing relapse of major depressive episodes. In this pilot study, we examined whether antidepressant response achieved through repeated ketamine infusions could be maintained with BA. Methods: In this case series, patients with treatment-resistant depression who met antidepressant response criteria in a clinical trial of repeated ketamine infusions subsequently completed 12–17 sessions of BA. Depressive symptoms were measured at each session with the Beck Depression Inventory-II (BDI-II). Secondary outcomes included changes in work and social adjustment, suicidal ideation, and anxiety. Results: Ten of the 13 participants who initiated BA completed the full course of psychotherapy. These participants showed significant improvement in self-reported depressive symptoms (p = 0.007) and work and social adjustment scores (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
