Prognosis and causes of death of patients with acute exacerbation of fibrosing interstitial lung diseases
Autor: | Riitta Kaarteenaho, Risto Bloigu, Johanna Salonen, Minna Purokivi |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: | |
Zdroj: | BMJ Open Respiratory Research, Vol 7, Iss 1 (2020) |
Druh dokumentu: | article |
ISSN: | 2020-0005 2052-4439 |
DOI: | 10.1136/bmjresp-2020-000563 |
Popis: | BackgroundThe aim of this study was to compare the clinical characteristics, causes of death and factors impacting on the prognosis of patients with idiopathic pulmonary fibrosis (IPF) and other fibrosing interstitial lung disease (FILD) with a history of acute exacerbation (AE) of IPF or FILD.MethodsRetrospective data of hospital treatment periods caused by AE-IPF and AE-FILD were collected from medical records. Clinical features and survival data of IPF and non-IPF cases were evaluated and compared. The underlying and immediate causes of death were gathered from death certificates.ResultsA total of 128 patients fulfilled the criteria for inclusion. IPF (n=79/62%), rheumatoid arthritis-associated interstitial lung disease (RA-ILD; n=17/14%) and asbestosis (n=11/8.6%) were the most common FILD subgroups in the study. The median survival after hospitalisation in AE-IPF was 2.6 months compared with 21 months in other AE-FILDs (p |
Databáze: | Directory of Open Access Journals |
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