3D bioprinting of high cell-density heterogeneous tissue models through spheroid fusion within self-healing hydrogels

Autor: Andrew C. Daly, Matthew D. Davidson, Jason A. Burdick
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-21029-2
Popis: Cellular models are needed to study disease in vitro and to screen drugs for toxicity and efficacy. Here the authors develop a bioprinting approach to transfer spheroids into self-healing support hydrogels at high resolution, which enables their patterning and fusion into high-cell density microtissues of prescribed spatial organization.
Databáze: Directory of Open Access Journals