Enhanced oral bioavailability and prophylactic effects on oxidative stress and hepatic damage of an oil solution containing a rosmarinic acid–phospholipid complex

Autor:	Jun-Hui Yang, Liang Zhang, Jun-Song Li, Li-Hua Chen, Qin Zheng, Ting Chen, Zhi-Peng Chen, Ting-Ming Fu, Liu-Qing Di
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	Rosmarinic acid Phospholipid complex Oil solution Antioxidant activity Bioavailability Nutrition. Foods and food supply TX341-641
Zdroj:	Journal of Functional Foods, Vol 19, Iss , Pp 63-73 (2015)
Druh dokumentu:	article
ISSN:	1756-4646
DOI:	10.1016/j.jff.2015.09.013
Popis:	Rosmarinic acid (RA) is an important naturally occurring polyphenol from plants of the mint family with many health-promoting benefits, but these can be influenced by its poor bioavailability. In this study, the bioavailability and bioefficacy of RA as RA–phospholipid complex (RA–PLC) and as RA–PLC oil solution (RA–PLC–ME) were evaluated. Evaluations in Caco-2 cell monolayers in vitro revealed that the membrane permeability of RA–PLC and RA–PLC–ME was significantly increased (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/3e852b2658e34e5989f6720f8711d835 Zobrazit plný text záznamu Full Text from ScienceDirect View record in DOAJ