Approaches for the synthesis, chemical modification and biological properties of N-acylphenothiazines
| Autor: | Iryna Myrko, Taras Chaban, Yulia Matiichuk, Mohammad Arshad, Vasyl Matiychuk |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Current Chemistry Letters, Vol 10, Iss 4, Pp 377-392 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1927-7296 1927-730X |
| DOI: | 10.5267/j.ccl.2021.5.005 |
| Popis: | In this review we systematized the theoretical and experimental data concerning the versatile approaches for the synthesis of N-acylphenothiazines. The aim of the study was to compile the literature reported worldwide in the past 20 years. This article also reviewed the analysis of pharmacological activities of these heterocycles as one of the promising chemotherapeutic objects for the modern bioorganic and medicinal chemistry. It has been hypothesized that the enormous biological potential of these moieties is due to the radical nature in the acyl moiety. Therefore, the present review will be a good contribution to the literature and will provide the platform for the medicinal chemistry researchers to carry out more studies aiming the N-acylphenothiazine moieties as the novel chemotherapeutic agents. |
| Databáze: | Directory of Open Access Journals |
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