Epilepsy in mitochondrial diseases. Clinical lecture
Autor: | A. S. Kotov, K. V. Firsov |
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Jazyk: | ruština |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Русский журнал детской неврологии, Vol 17, Iss 4, Pp 63-70 (2023) |
Druh dokumentu: | article |
ISSN: | 2073-8803 2412-9178 |
DOI: | 10.17650/2073-8803-2022-17-4-63-70 |
Popis: | Mitochondrial dysfunction mainly affects organs with high metabolic demand, primarily the brain. Epilepsy is a common phenotypic sign of both syndromic and non-syndromic mitochondrial diseases. Epilepsy in mitochondrial diseases is poorly treatable and is often an unfavorable prognostic sign. Patients with mitochondrial epilepsy are prescribed various anti-seizure medications. Mitochondriotoxic drugs should be avoided. Descriptions of MELAS-syndrome, MERRF-syndrome, Leigh-syndrome, NARP-syndrome are given. |
Databáze: | Directory of Open Access Journals |
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