Impact of chronic obstructive pulmonary disease on linear and nonlinear dynamics of heart rate variability in patients with heart failure

Autor: C.L. Goulart, F.R. Caruso, G.P.T. Arêas, P.B. dos Santos, P.F. Camargo, L.C.S. de Carvalho, M.G. Roscani, R.G. Mendes, A. Borghi-Silva
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Brazilian Journal of Medical and Biological Research, Vol 54, Iss 2 (2020)
Druh dokumentu: article
ISSN: 1414-431X
1414-431x
DOI: 10.1590/1414-431x202010084
Popis: The objective of this study was to investigate the impact of chronic obstructive pulmonary disease (COPD)-heart failure (HF) coexistence on linear and nonlinear dynamics of heart rate variability (HRV). Forty-one patients (14 with COPD-HF and 27 HF) were enrolled and underwent pulmonary function and echocardiography evaluation to confirm the clinical diagnosis. Heart rate (HR) and R-R intervals (iRR) were collected during active postural maneuver (APM) [supine (10 min) to orthostasis (10 min)], respiratory sinus arrhythmia maneuver (RSA-M) (4 min), and analysis of frequency domain, time domain, and nonlinear HRV. We found expected autonomic response during orthostatic changes with reduction of mean iRR, root mean square of successive differences between heart beats (RMSSD), RR tri index, and high-frequency [HF (nu)] and an increased mean HR, low-frequency [LF (nu)], and LF/HF (nu) compared with supine only in HF patients (P
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