Depth of Anesthesia as a Risk Factor for Perioperative Morbidity

Autor: Argyro Petsiti, Vassilios Tassoudis, George Vretzakis, Dimitrios Zacharoulis, Konstantinos Tepetes, Georgia Ganeli, Menelaos Karanikolas
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Anesthesiology Research and Practice, Vol 2015 (2015)
Druh dokumentu: article
ISSN: 1687-6962
1687-6970
DOI: 10.1155/2015/829151
Popis: Introduction. The prognostic value of age, physical status, and duration of surgery on perioperative course has been extensively studied. However, the impact of deep hypnotic time (time when Bispectral Index values are less than 40) has not been well evaluated. Methods. We designed an observational study to clarify the relative influence of deep hypnotic time (DHT) on outcome. Eligible participants were mentally stable patients over 18 years old scheduled for elective major abdominal surgery. In total, 248 patients enrolled. Data were analyzed using Fisher’s exact test and multiple logistic regression. Results. Five variables (DHT, hypotension, age, comorbidity, and duration of surgery) showed statistically significant association with complications, when examined independently. However, when all variables were examined together in a multiple logistic regression model, age and comorbidity were no longer associated with outcome. DHT, hypotension, and duration of surgery were significant predictors of “complications,” and “hypotension” was a significant predictor of prolonged hospital stay (P
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