Fulminant Herpes Simplex Hepatitis Secondary to Adalimumab in Crohn’s Disease: A Case Report

Autor:	Kanika Goel, Mark Bunker, Anna Balog, Jan F Silverman
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Medicine (General) R5-920
Zdroj:	Clinical Medicine Insights: Case Reports, Vol 12 (2019)
Druh dokumentu:	article
ISSN:	1179-5476 11795476 40148416
DOI:	10.1177/1179547619858979
Popis:	Herpes simplex virus (HSV) hepatitis is an uncommon cause of fulminant hepatic failure, seen mostly in immunocompromised patients. Conventional treatment modalities for inflammatory bowel disease (IBD), such as steroids and azathioprine, have been known to cause HSV hepatitis. However, the reported incidence of HSV hepatitis in IBD patients undergoing tumor necrosis factor (TNF)-α inhibitor therapy is very rare. In this case report, we describe a rare case of fulminant HSV hepatitis that developed in a patient with Crohn’s disease after treatment with the TNF-α inhibitor, adalimumab.
Databáze:	Directory of Open Access Journals
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