Evaluation of Postural Parathyroid Hormone Change in Patients with Primary Hyperparathyroidism

Autor: Cevdet Aydin, Sefika Burcak Polat, Ahmet Dirikoc, Berna Ogmen, Neslihan Cuhaci, Reyhan Ersoy, Bekir Cakir
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: International Journal of Endocrinology, Vol 2014 (2014)
Druh dokumentu: article
ISSN: 1687-8337
1687-8345
DOI: 10.1155/2014/628010
Popis: Purpose. In the present study, we aimed to investigate postural change of PTH in normal individuals and in patients with primary hyperparathyroidism (PHPT). Methods. Twenty-two patients with PHPT and nine healthy controls were enrolled. Following 12 h of fast, patients stayed in recumbent position for an hour and PTH and total Ca measurements were performed at the 45th and 60th minutes of resting. Afterwards, the patients resumed an upright posture for an hour and again blood samples were taken at the 45th and 60th minutes of standing. Results. In the PHPT group, mean PTH was calculated as 153.9 pg/mL in the recumbent position while it was 206.3 during upright position (Δ change was 47.7) (P
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