The CD271 expression could be alone for establisher phenotypic marker in Bone Marrow derived mesenchymal stem cells.
| Autor: | Antonio Carrasco-Yalan, Oscar R Gonzalez-Ramella, Arturo Orozco-Barocio, Edgardo Flores-Torales, Karlen Gazarian, Silvio Cuneo-Pareto |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Folia Histochemica et Cytobiologica, Vol 48, Iss 4, Pp 682-686 (2011) |
| Druh dokumentu: | article |
| ISSN: | 0239-8508 1897-5631 |
| DOI: | 10.5603/4185 |
| Popis: | Mesenchymal stem cells (MSCs) are of great interest for their potential use in cellular therapies. To define the population more precisely, diverse surface markers have been used. We propose here to use CD271 as the sole marker for MSCs in fresh bone marrow. We compared CD271+ populations to the presence or absence of five defined markers for MSCs: CD90+, CD105+, CD45-, CD34- and CD79. The correlations between markers were evaluated and analyzed with a Pearson's correlation test. We found that the average percentage of cells expressing the combination of markers CD90+, CD105+, CD45-, CD34- and CD79- was 0.54%, and that the average percentage average of CD271+ cells was 0.53%. The results were significant (p |
| Databáze: | Directory of Open Access Journals |
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