Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis

Autor: Hassan Riad, Haya Al Mannai, Khalid Mansour, Khalifa Al Qaatri, Sharifa Al Dosari, Amina Al Obaidaly, Emad Sultan
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Case Reports in Dermatology, Vol 5, Iss 2, Pp 225-231 (2013)
Druh dokumentu: article
ISSN: 1662-6567
DOI: 10.1159/000354767
Popis: Alopecia areata and vitiligo are autoimmune diseases, both associated with multiple autoimmune comorbidities. Many studies show colocalization of these diseases at the same anatomical site. Here, we have a case where both disorders were reported to present in the same patient. Diphenylcyclopropenone (diphencyprone, DCP) is used in the treatment of alopecia areata and may induce vitiligo in some patients. We report on one case of vitiligo that was induced by DCP during therapy for alopecia universalis. Alopecia areata and vitiligo share many susceptibility genes. Follicular melanocyte destruction may represent the link between the two diseases.
Databáze: Directory of Open Access Journals