Lax skin and blurring of vision- A case report of pseudoxanthoma elasticum

Autor: Murali Narasimhan, R Ramachandran, J Samuel Cornelius Gnanadurai, Priya Cinna T Durai, P Kalaivani, C Nithila
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Family Medicine and Primary Care, Vol 11, Iss 12, Pp 7972-7974 (2022)
Druh dokumentu: article
ISSN: 2249-4863
DOI: 10.4103/jfmpc.jfmpc_2337_21
Popis: Increased laxity of the skin can be caused by aging, significant weight loss, or defects in the elastic tissue. A 38-year-old female presented with increased laxity of the skin over the neck, thighs, and abdomen for 6 years, associated with headache and blurring of vision for a week. On cutaneous examination, prominent skin folds, laxity, and wrinkles were noted over the neck, abdomen, thighs, and groin, with yellowish papules along the neck creases. Ocular examination revealed features suggestive of angioid streaks. Skin biopsy showed fragmented elastic fibers and intervening calcium deposits on Verhoeff Van Gieson and Von Kossa stains. Based on these findings, a diagnosis of pseudoxanthoma elasticum (PXE) was made. The patient was started on oral and topical sunscreens and eye protection and advised regular follow-up. Diagnosing the condition early based on skin findings can help prevent further multi-system manifestations by taking appropriate preventive measures as this condition is progressive and has no cure.
Databáze: Directory of Open Access Journals
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