Biomarkers in inflammometry pediatric asthma: utility in daily clinical practice

Autor: Silvia Sánchez-García, Alicia Habernau Mena, Santiago Quirce
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: European Clinical Respiratory Journal, Vol 4, Iss 1 (2017)
Druh dokumentu: article
ISSN: 2001-8525
20018525
DOI: 10.1080/20018525.2017.1356160
Popis: Asthma is a common disease in both high and lower income countries that starts early and persists often for life. A correct and accurate diagnosis, treatment and follow-up during childhood are essential for a better understanding of adult asthma and avoiding over- or under-treatment. Th2 inflammation in children with asthma symptoms is usually assessed by measuring with serum total IgE, blood eosinophilia and FeNO levels that may help to predict asthma, particularly in those infants and young children in whom lung function tests are difficult to perform. FeNO measurement, compared to intra-individual levels, may be useful also for ascertaining treatment adherence. Nevertheless, an isolated measurement may be insufficient and only the combination of these markers improves the diagnosis, phenotyping and follow-up of an asthmatic child.
Databáze: Directory of Open Access Journals