Nonalcoholic Fatty Liver Disease in Chronic Hepatitis B and C Patients from Western Amazon
| Autor: | A. C. M. Nascimento, D. R. Maia, S. M. Neto, E. M. Lima, M. Twycross, R. F. Baquette, C. M. O. Lobato |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: | |
| Zdroj: | International Journal of Hepatology, Vol 2012 (2012) |
| Druh dokumentu: | article |
| ISSN: | 2090-3448 2090-3456 |
| DOI: | 10.1155/2012/695950 |
| Popis: | Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of histological conditions, extending from simple steatosis to end-stage liver failure. The aim of this study was to examine the prevalence of NAFLD and its associations in chronic hepatitis B and C patients. Methods. We included all patients diagnosed with chronic hepatitis B and C who underwent a liver biopsy between January 2010 and October 2011 (n = 104). Parameters studied included hepatitis type, anthropometric data, histologic, hepatic, metabolic and lipid assessments, presence of hypertension and viral load. Results. Hepatitis B was presented in 28.8% (n = 30) of patients, while hepatitis C was presented in 71.2% (n = 74). In addition, hepatic steatosis was present in 25% (n = 26) of the patients. Steatosis was frequently found in hepatitis C patients (31.1%; 25% n = 23), but infrequently in hepatitis B patients (10%; n = 3) (P = 0.024). It was also found that steatosis was frequently present in hepatitis C patients with intense fibrosis (52.94%) (P = 0.025). Discussion. Our results suggest that steatosis is a common feature in patients with viral chronic hepatitis, and that it plays a different role in each type of hepatitis. |
| Databáze: | Directory of Open Access Journals |
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